T cell activation assay: preclinical research

Newsletter

Target NeuroInflammation:
A practical applications newsletter for inflammations and neurology research.

Register


More Information

Cytokine-stimulated bronchial smooth muscle cell in vitro assay

Preclinical in vitro screening assay for compounds involved in respiratory diseases.

In vitro cytokine-stimulated bronchial smooth muscle assay    Get Proposal
Cell System Human bronchial smooth muscle cells (BSMC)
Length 1 week
Stimulant cytokines (IL-1b and/or TNF-a)
Reference Dexamethasone
Readouts

PGE2, eotaxin, RANTES, IL-6

 


cytokine-stimulated bronchial smooth muscle cell assay - MD Biosciences preclinical contract research (CRO)

Figure: BSMCs were stimulated with IL-1b or TNFa. Cell culture supernatants were assayed for IL-6, RANTES, eotaxin and PGE2 using a multiplex assay. Mean values are shown. Error bars represent standard deviations. 


Interesting Fact

Preclinical drug discovery and development outsourcing can lower development costs, decrease risk, speed up timelines and increase the confidence of potential partners.

Client Testimonial

“Among all the CROs that I have used over the years, including recently for inflammation, MD Biosciences has been one of the very best in terms of scientific knowledge, expertise, data quality, timelines, flexibility and personal contacts.”

O.B., Director of Preclinical Research Pharmaceutical Company