histology and immunohistochemistry services

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Target Inflammation:
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Related Assays

Gene Expression Biomarker Analysis
Biomarker Analysis
Inflammation Models
Neurology Models

Histological & Immunohistochemical Analysis

MD Biosciences provides histological and immunohistochemical analysis as an endpoint for in vivo disease models. Staining procedures include but are not limited to:

  • LFB staining
  • H&E staining
  • Washed H&E
  • Luna staining
  • Sirius red
  • PAS staining

 

H&E Staining: Insulitis   (click on thumbnail images)
Normal islet Insulitis Insulitis Islet Degeneration Islet Degeneration

 

LFB Staining: Longitudinal Sections of Vertebral Column & Spinal Cord from MOG-EAE    (click on thumbnail images)
Normal islet white matter white matter white matter White matter

 

H&E Staining: Longitudinal Sections of Cervicothoracic Vertebral Column & Spinal Cord from MOG-EAE    (click on thumbnail images)
Histology histology histology histology histology
histology histology histology histology histology
histology histology      

 

H&E Staining: Joints from Collagen Antibody Induced Arthritis (CAIA) Model (click on thumbnail images)   
erosion infiltration deposition pannus formation synovial hyperplasia

 

 



 


 

Interesting Fact

Multiple Sclerosis is a lifelong ailment that affects more than 400,000 Americans, resulting in an earning loss of about $10.6 billion annually for U.S. families with MS.

Client Testimonial

“Among all the CROs that I have used over the years, including recently for inflammation, MD Biosciences has been one of the very best in terms of scientific knowledge, expertise, data quality, timelines, flexibility and personal contacts.”

O.B., Director of Preclinical Research Pharmaceutical Company