Lung Inflammation is a critical component of many lung diseases including asthma. Asthma is classified as a chronic inflammatory disease of the airways, however the underlying physiology and immunological pathways are not completely understood. Allergan challenge models are commonly used to study mechanisms involved in lung inflammation and allergic asthma. Ovalbumin-induced allergic asthma is a widely used model to reproduce the airway eosinophilia, pulmonary inflammation and elevated IgE levels found during asthma.
MD Biosciences offers models to study the inflammatory components involved in lung inflammation and asthma. Don't see a readout or model listed below? Our scientists are experienced in validating models quickly from the literature. Contact a scientist to discuss your model requirements.
|Biologics||Biomarkers in BALF||Tissue biomarkers|
|NCEs||FACS analysis of BALF||Histology/IHC|
|Plant-based compounds||Body Weights||PK|