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Immunology/Inflammation Laboratory Services

Rheumatoid Arthritis Research

Inflammatory Joint Disease Models

Pharmacology & Efficacy Studies for Rheumatoid Arthritis

Rodent models of immune-mediated arthritis (RMIA) are commonly used to evaluate the mechanisms of inflammatory joint disease, as well as test the efficacy of anti-arthritic compounds. Collagen induced arthritis (CIA) and adjuvant induced arthritis (AIA) are two commonly used models for this purpose. At MD Biosciences we offer our clients the novel and rapid collagen antibody-induced arthritis (CAIA) model as well.

Our expertise includes:

See below information to learn more about our experience/readouts/options: 

 

Experience Readouts Options
Biologics Arthritis score Biomarkers (protein, mRNA)
NCEs Paw thickness Cell populations by FACS
Plant-based compounds Body Weights Histology/IHC
siRNA   PK
    Pain