Model of Gastrointestinal Inflammation and Crohn's Disease
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Colonic Sections from TNBS-Induced IBD Model in Mice Processed via "Swiss Roll" Technique to Preserve Morphology (Periodic Acid Schiff/PAS Staining):
Figure A. Medium magnification of PAS-stained colon sections demonstrating mucins and polysaccharides. Figure B. High magnification of PAS-stained section in A.
Balb/c were administered TNBS intra-rectally. Over the course of 7 days, colitis score was monitored in animals receiving vehicle and positive controls anti-IL-12 p40.