Preclinical contract research 

Neurology and CNS Research

Advancing Neuro/CNS innovations

Neurological and CNS Preclinical Services

Neurology discoveries through preclinical research

 

Our CNS disease preclinical research services are provided from our dedicated Neurology laboratories. Our state of the art laboratories are fitted with the most advanced equipment and staffed with experienced scientists to provide the best methodologies. Wherever possible, we include clinically-relevant read-outs, such as with the use of the Neurometer® CPT®  (Neurotron, Inc.) a unique neurodiagnostic device that painlessly evalutes the functioning of small unmylenated (C), small myelinated (Aδ) and large myelinated (Aβ) sensory nerve fibers at any cutaneous site. The Neurometer® CPT® device is sensitive to both hypoesthetic and hyperesthetic abnormalities and has more than 800 peer reviewed research publications documenting its clinical diagnostic capabilities. 

Neurodegenrative diseases including Parkinson's Disease as well as neuro-inflammation related models such as EAE for multiple sclerosis (MS) and ischemia take center stage. Our laboratories are also proud to be known as a center of excellence in the study of neuropathic, chronic pain as well as acute pain with multiple validated models and relevant read-outs. Our pain services are extended with unique pig translational models complementing our rodent studies and offering confidence as compounds move to IND and clinical stages of their development.

Are you interested in developing new models or variations of already established models? Call us now to discuss our possibilities and suggestions. We would be interested in co-development and piloting new methodologies to advance this exciting area.

We've collaborated with many biopharmaceutical companies to advance their Neuro/CNS innovations through preclinical efficacy phases. Whether the objective be to bring a compound to outlicensing stages, expand the therapeutic potential of already approved therapies or progress a compound to clinical trial phases, MD Biosciences can help. We are more than just a CRO, we are a research partner that can help design the studies based on the goals at hand. We understand the time and budget contraints that every research group is working under, whether you are a large pharma company or a small start-up. All studies are designed to maximize the amount of data that can be obtained from a single animal or cell. 

What will we bring to your project?

  • Flexibility to accomodate last minute study changes
  • Open communication so you know the status during your study
  • Scientific contribution to the study design
  • Innovative approaches to tackling problems
  • Wide range of ex vivo analysis including multiplex, PCR, histology, IHC
  • Wide range of behavior, cognitive and motor function tests
  • Willingness to validate new methods
  • IACUC and AAALAC oversight
  • GLP-like processes to bring quality and consistency to methods
How can you be sure? We'd be happy to share experiences from our sponsors. Just ask. 

 

Request Study Proposal

 


CONTACT US:

1-888-USMDBIO
+41-44 986 2628
email us