<img height="1" width="1" style="display:none;" alt="" src="https://dc.ads.linkedin.com/collect/?pid=217082&amp;fmt=gif">

Preclinical Laboratory Services

Neurology and Central Nervous System Research

Advancing Neurological & CNS Innovations

Neurological Disease Models and CNS Studies

MDB offers neurological and CNS research services through our dedicated Neurology Laboratories. Our state-of-the-art facilities are fitted with modern, highly-sensitive equipment for use in preclinical and translational studies, and are staffed with experienced PhD-level scientists to apply optimal methodologies in the proper context. Wherever possible, we include clinically-relevant read-outs with the application of such technologies as the Neurometer® CPT® (Neurotron, Inc.), a unique neurodiagnostic device that painlessly evalutes the functioning of small unmylenated (C), small myelinated (Aδ) and large myelinated (Aβ) sensory nerve fibers at any cutaneous site. The Neurometer® CPT® is sensitive to both hypoesthetic and hyperesthetic abnormalities, and has more than 800 peer reviewed research publications documenting its clinical diagnostic capabilities. 

Neurodegenerative diseases like Parkinson's as well as neuro-inflammatory diseases such as multiple sclerosis (MS) take center stage, with additional capabilities in stroke and cerebral ischemia. Our laboratories are also proud to be known as a center of excellence in the study of neuropathic, chronic and acute pain, offering multiple validated models and relevant pain read-outs. Our pain services are extended with unique pig translational models complementing our rodent studies and offering confidence as compounds move to IND and clinical stages of their development.

Are you interested in developing new models or variations of already established models? Call us now to discuss our possibilities and suggestions. We would be interested in co-development and piloting new methodologies to advance this exciting area.

We've collaborated with many biopharmaceutical companies to advance their Neuro/CNS innovations through preclinical efficacy phases. Whether the objective be to bring a compound to outlicensing stages, expand the therapeutic potential of already approved therapies or progress a compound to clinical trial phases, MD Biosciences can help. We are more than just a CRO, we are a research partner that can help design the studies based on the goals at hand. We understand the time and budget contraints that every research group is working under, whether you are a large pharma company or a small start-up. All studies are designed to maximize the amount of data that can be obtained from a single animal or cell. 

What will we bring to your project?

  • Flexibility to accomodate last minute study changes
  • Open communication so you know the status during your study
  • Scientific contribution to the study design
  • Innovative approaches to tackling problems
  • Wide range of ex vivo analysis including multiplex, PCR, histology, IHC
  • Wide range of behavior, cognitive and motor function tests
  • Willingness to validate new methods
  • IACUC and AAALAC oversight
  • GLP-like processes to bring quality and consistency to methods
How can you be sure? We'd be happy to share experiences from our sponsors. Just ask. 

 

Request Study Proposal

 Scientists-Smiling-Laboratory-Clinical-Research.jpg

CONTACT US:


+1-651-641-1770

1-888-876-3246

+41-44-986 2628


Email Us