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MD Biosciences Announces Release of Zika Virus Diagnostic Test

Posted by MD Biosciences on Feb 29, 2016 2:00:00 PM

Zika Virus Test Update: Saint Paul, MN March 10, 2016

MD Biosciences announces that it will proceed with the Zika test services following clarification with the FDA regarding any pre-market approval requirements pertaining to this assay. Testing services will not be offered pending this clarification.

 

Saint Paul, MN, USA - February 29, 2016, - MD Biosciences, Inc. (mdbiosciences.com) Clinical and Diagnostics Services Laboratory announces the release of its rapid assay to detect the virus in human blood and urine samples. The nucleic acid test can be performed in a few hours in blood, plasma, serum or urine samples. The test is specific for the Zika virus and was shown not to cross react with other infectious viruses such as Dengue, West Nile or Chikunguya. The laboratory developed test is available immediately

The World Health Organization stated that the spread of the mosquito-borne virus will grow explosively throughout the Americas. According to the CDC, the virus has also been shown to be transmitted through sexual contact. Upwards of four million infections are expected in the region. Close to 80% of infections are asymptomatic while others suffer from fever, rash, joint aches and other hallmarks. A steep increase in birth defects and Guillain-Barre syndrome has correlated to the spread of the virus. The explosive spread of the virus, along with major crowd and traveller-related events such as this year’s Olympic Games in Brazil, have underscored the need for steps in fighting the spread of the virus, including the ability to rapidly and specifically identify the infection.

Eddie Moradian, Chief Executive Officer at MD Biosciences, stated, “We are extremely proud of our CLIA diagnostics laboratory’s ability to provide a reliable, accurate and rapid method of testing for Zika virus. This demonstrates our commitment in placing our expertise, knowledge and infrastructure for the betterment of health, in the US and throughout the world, whether through the development of more advanced diagnostics or by advancing newer, better and more efficient therapies."

 

About MD Biosciences

MD Biosciences is a leading provider of clinical and preclinical services with over 25 years of experience in the clinical diagnostics and preclinical research areas. Services are provided for cancer, inflammatory, metabolic and neurological diseases. MD Biosciences laboratories provide extensive experience in working with biomarkers and developing validated laboratory assays. MD Biosciences operates through its facilities and laboratories in the United States, Switzerland and Israel.

Located in Saint Paul, MN, MD Biosciences' Clinical and Diagnostics Services Laboratory is a CLIA accredited laboratory for high complexity testing. All testing is performed under stringent guidelines in state of the art laboratories. Other services include clinically relevant tests for genetic markers of diseases including various cancers.

Inquiries may be directed to: Susan Belzer, Vice President, MD Biosciences Clinical Diagnostics Laboratory

by e-mail: clinlab@mdbiosciences.com

by telephone to 1-888-USMDBIO (1-888-876-3246) or (651-641-1770).

 

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Topics: news, Preclinical Discovery, Zika, Virus Test

MD Biosciences Announces Addition of Cancer Suite

Posted by MD Biosciences on Jan 28, 2016 4:28:59 PM

ST. PAUL, Minnesota - January 25, 2016 - MD Biosciences (mdbiosciences.com) today announced the addition of its suite of in vivo and in vitro cancer models to its family of preclinical contract research services. MD Biosciences' oncology research program specializes in murine solid tumors for subcutaneous and orthoptopic models (for example, advanced breast cancer and renal cancer) with a specific focus on the immune aspects of disease development and progression. The comprehensive services include both syngeneic and xenograft models with readouts for longitudinal tumor monitoring (for some models), longitudinal blood phenotyping (immune cell distribution, biomarkers, etc.), endtime-point primary/metastic tumor evaluation, tumor tissue-specific cellular analysis using intravascular staining (cells: epithelial, endothelial, immune, etc.), biomarker analysis (blood, tumor, tissue, spleen, lymph node, etc.) and histological grading and evaluation of tumor specific issue (H&E, IHC, etc.).

"Our onco-immunology research team is comprised of skilled scientists with deep-rooted expertise in a highly complex field," said Eddie Moradian, MD Biosciences CEO. "We at MD Biosciences are excited to bring our high level of expertise and our novel models to assist sponsors and partners in reaching their programs' developmental goals. This new suite of capabilities compliments our existing, best-in-class services in other disease areas.

 

About MD Biosciences

MD Biosciences is a leading provider of preclinical services in the core areas of inflammation, immunological, neurologoical and metabolic diseases. The suite of services includes a wide range of cell-bassed assays, in vivo disease models, translational models as well as models for the indentification of the mode of action of drugs. The services are supported by CLIA accredited and GLP in vitro diagnostic laboratories for the testing of samples by using genomic and proteomic methods. MD Biosciences' in vitro laboratories provide services for the testing of clinical samples. Proprietary models include pig models for neuropathic pain, would healing and other key disease areas.

 

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Topics: news, in vivo pain models, cancer/tumor, contract research

MD Biosciences Releases NeuroFreeze | Preserve Primary Neurons

Posted by MD Biosciences on Apr 7, 2015 8:47:00 PM

Zurich, Switzerland, April 1, 2015 – MD Biosciences, a global biotechnology company focused in neuroscience research, announces the launch of its new NeuroFreeze media for the freezing and culturing of rat and mouse hippocamal or cortex neurons. The proprietary freezing medium retains high viability, between 75-90%, and maintains all the expected characteristics of primary neurons in culture. 

Primary neurons from mice are a good model system to examine the structure and function of neurons and have been widely used very successfully by the neuroscience community. However, they are cumbersome to culture, need to be cultured directly from mice or rats and any excessive neurons that cannot be used need to be discarded leading to loss of precious tissue and unnecessary animal sacrifice. We have developed a proprietary freezing medium that allows these neurons to be frozen and cultured as required, an advantage to institutions striving to adhere to the principals of the 3Rs with emphasis on minimizing animal use for the only purpose of harvesting neurons.

preservedneurons 

Benefits of NeuroFreeze Freezing Medium:

  • Retain 75-90% viability of neurons
  • Maintain all expected characteristics of primary neurons, including morphology and expression of neuronal and synaptic markers
  • Eliminates lengthy stepwise termperature reduction protocols as with other preserving medium 

 

The use of NeuroFreeze media offers the convenience of thawing and using neurons as need arises without having to dissect an animal for neuron culture each time experiments need to be conducted. This would allow researchers to freeze neurons from control or diseased mice and culture them as necessary, a great advantage for researchers using mouse models of disease, or genetically engineered strains.

 

About MD Biosciences

MD Biosciences offers products for use in the inflammations, neurology, endocrinology, and metabolic disorders research fields. At MD Biosciences, we partner with the pharmaceutical, biotech, academic and government communities to provide the products needed with a client-focused approach. Our goal is to assist you in optimizing your own research process and reaching your objectives faster.

 

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The information in this press release should be considered accurate only as of the date of the release. MD Biosciences has no intention of updating and specifically disclaims any duty to update the information in these press releases.

 

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Topics: Research Products, Neuropathy

MD Biosciences & Janssen R & D, LLC to screen extensive library of compounds.

Posted by MD Biosciences on Apr 14, 2014 8:00:00 AM

MD Biosciences enters into an agreement with Janssen Research & Development, LLC to screen an extensive library of compounds with its proprietary Senerga® Phenotypic Screening Platform.

 

St Paul, MN (April 14, 2014) – MD Biosciences announces that it has entered into a research agreement with Janssen Research & Development, LLC, through the Janssen Incubator and a venture team focused on natural product drug discovery programs, to screen a novel and proprietary chemical library of compounds for pharmaceutically relevant activity.  MD Biosciences will apply its innovative screening platform, Senerga® Phenotypic Screening Platform for this purpose. Senerga® PSP is based on three matrices covering  pathways related to inflammatory, metabolic, cardiovascular and CNS diseases in addition to delivering preliminary toxicology data. Senerga® PSP delivers a comprehensive portfolio of phenotypic and biomarker data for each compound in the library and points towards putative mode of action of novel compounds. A dedicated scoring algorithm is used to rank compounds with regards to their activity. Pharmaceutically active compounds will be validated in dedicated disease models. The use of Senerga® PSP provides unique speed and efficiency in mining its novel chemical library.

 

About the Senerga® Screening Platform

MD Biosciences has in-depth expertise and data on complex programs involving mechanism of action and efficacy studies. Senerga®PSP provides a uniquely customized approach applicable to new compounds as well as for repositioning of failed or on-market drugs. Senerga® is available for collaborative development programs together with pharmaceutical and biotechnology companies.

 

About MD Biosciences

MD Biosciences is dedicated to the preclinical discovery and development of compounds. The company engages in collaborative partnerships and research projects with pharmaceutical and biotechnology companies world wide. MD Biosciences operates purpose-built and state-of-the-art facilities in Nes Ziona, Israel and in St. Paul, MN, USA.

 

 

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The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

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Topics: CRO/outsourcing, news

MD Biosciences Receives AAALAC Accreditation

Posted by MD Biosciences on Mar 19, 2014 12:59:00 PM

Wednesday, March 19, 2014, St. Paul, MN – MD Biosciences, a drug discovery and development services provider, is pleased to announce it has been give full accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC). Accreditation for the St Paul facility was awarded following an extensive on-site assessment by representatives of the Council on Accreditation, which stated that MD Biosciences “provides and maintains an excellent program of laboratory animal care and use” with particular noteworthiness in the program alignment with quality animal care and use, comprehensive occupational health and hazard reduction, high level of attention to detail in documentation and standard operating procedures as well as staff training programs and a high level of expertise among the personnel. 

 

“We are very pleased to receive accreditation from AAALAC, recognizing that only 900+ institutions worldwide carry this accreditation. MD Biosciences prides itself on high standards both in scientific methods and animal care. This accreditation provides our clients assurance of our commitment to compliance with industry and regulatory guidelines for high standards of animal care and handling” said Eddie Moradian, CEO of MD Biosciences. Researchers can read further about the benefits of accreditation here.

 

MD Biosciences is also committed to its continuing development and expansion of services it offers its clients and partners from its multiple laboratories. In addition to specialized efficacy studies and the development of more clinically relevant models, MD Biosciences also offers its partners customized screening programs aligned with clients’ specific business goals.

 

 

 About AAALAC International

AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC stands for the "Association for Assessment and Accreditation of Laboratory Animal Care." More than 900 companies, universities, hospitals, government agencies and other research institutions in 37 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. These institutions volunteer to participate in AAALAC's program, in addition to complying with the local, state and federal laws that regulate animal research.

www.aaalac.org

 

About MD Biosciences

MD Biosciences is a leading preclinical research group and contract research organization (CRO) working with biopharmaceutical and medical device companies in an effort towards progressing discovery and development programs to clinical stages. We are deeply focused on inflammatory, neurodegenerative/CNS, pain, dermal, metabolic and cardiovascular conditions with a particular emphasis on the interplay between the immune, nervous and cardiovascular systems and the conditions that arise in the cross talk between them. We bring decisive value to our clients’ programs with the extensive experience gained over many years of handling different compound classes and numerous therapeutic indications. MD Biosciences operates three state-of-the-art laboratories across the globe equipped with highly specialized infrastructure, equipment, methods and scientists with expertise in therapeutics areas. Find out more about MD Biosciences and the services offered at www.mdbiosciences.com.

 

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The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

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Topics: CRO/outsourcing, news

MD Biosciences Screens Large Pharma Co. Compounds w/its Senerga® Platform

Posted by MD Biosciences on Nov 4, 2013 1:49:00 PM

St Paul, MN  – MD Biosciences announces that it has entered into a research agreement with one of the Top 10 pharma companies for screening a library of compounds. MD Biosciences will apply its innovative screening platform, Senerga®, to the pharma company’s compound library with the primary objective of increasing the chances of discovery efficacy on a broader and more efficient basis. These compounds can then be selected based on pharmaceutically relevant activity to be further developed by the sponsor.

 

 “Exploring novel, high-value applications for compounds based on our Senerga® Platform is the core strength of MD Biosciences. We are very excited about this compay engaging MD Biosciences in this important program. It is a great company, sharing our vision in evolving new and efficient ways in the discovery process” said Eddie Moradian, CEO of MD Biosciences.

 

About the Senerga® Screening Platform

MD Biosciences has a long history of working on complex programs for mechnism of action screening, and efficacy. By conceptualizing a platform that provides algorithmic analysis of a combination of efficacy, biomarker, mechanistic and safety/behavior data, clients are able to broadly screen compounds on the basis of effects on cells, tissues and whole organisms in disease modification without the necessity of prior knowledge of therapeutic pathways. Senerga® screening is a customized approach through in vitro and in vivo models selected to give the broadest screen based on the compound library.

 

About MD Biosciences

MD Biosciences is a global preclinical research group and contract research organization (CRO) working with biopharmaceutical and medical device companies in an effort towards progressing discovery and development programs to clinical stages. MD Biosciences provides a broad range of services focused in inflammatory, neurodegenerative/CNS, pain, dermal, metabolic and cardiovascular conditions with a particular emphasis on the interplay between the immune, nervous and cardiovascular systems and the conditions that arise in the cross talk between them. Utilizing innovative approaches to efficacy and screening models, MD Biosciences has played a key role for our clients in multi-year programs that have involved respositioning/developing compounds, out-licensing compounds and screening compound libraries. MD Biosciences diverse portfolio of clients includes some of the world’s largest and most well-known pharmaceutical and biotechnology companies.

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The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

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Topics: news

MD Biosciences Syngeneic Tumor Models for Primary Orthotopic & Metastasis.

Posted by MD Biosciences on Oct 1, 2013 8:46:00 AM

syngeneic tumor models MDBiosciencesMD Biosciences releases a new line of in vivo syngeneic tumor models for the study of primary orthotopic tumors and metastasis. The basis of the syngeneic tumor model is that it uses tumor cells that are injected into either the organ of origin or into the systemic circulation of a host that is of the same species and genetic background as the tumor cells or tissue originated from. Additionally, syngeneic tumor models offer the advantage of a short latency time and increased phenotype reproducibility due to injecting a controlled number of cells.

Syngenic tumor models are excellent preclinical models for studying the interaction of tumor cells with the host immune system as well as the impact of tumors on local and systemic factors such as the surrounding tissue and the vascular system. They utilize injected tumor cells or tissue from the same species and genetic background as the host, which permits the assessment of compatible tumor-stroma microenvironmental interactions, endocrine signaling and immune responses. Unlike xenotransplantation models where the hosts are immunocompromised to enable the innoculation of human tumors or cells into murine hosts without rejection, syngenic tumor models utilize immuocompetent hosts allowing immune-cell-tumor-cell interactions. This is critical as a functioning immune system is the backbone of studies involving cytotoxic T cells, Tregs, tumor-associated macrophages, cell trafficking or inflammatory fibrotic stromal reactions. Additionally, the effects of an intact immune system on the onset of metastasis and progression are important.

Orthotopic Tumor models are created on the basis of injecting tumor cells directly into the organ of origin and exhibit organotypical interactions between the tumor cells and the surrounding stroma. These interactions affect the growth, differentiation and drug sensitivity of the tumor cells.

  • Breast Cancer
  • Liver Cancer/Hepatocellular carcinoma (HCC)
  • Neuroblastoma
  • Pancreatic Cancer

Metastasis Models are created on the basis of injecting tumor cells directly to the systemic circulation. The site of injection will largely dictate which metastasis will develop as the cells will arrest in the first capillary bed encountered.

  • Pulmonary metastasis
  • Hepatic metastasis

 

MD Biosciences research group is actively involved in developing approaches, methods and models that bring greater translational relevance to the clinical situation. With a high failure rate in the clinical trial phase of drug development, more relevant models are needed that provide greater translation to the clinic.

 

About MD Biosciences

MD Biosciences is a leading preclinical research group and contract research organization (CRO) working with biopharmaceutical and medical device companies in an effort towards progressing discovery and development programs to clinical stages. We are deeply focused on inflammatory, neurodegenerative/CNS, pain, dermal, metabolic and cardiovascular conditions with a particular emphasis on the interplay between the immune, nervous and cardiovascular systems and the conditions that arise in the cross talk between them. We bring decisive value to preclinical programs with the extensive experience gained over many years of handling different compound classes through all administration routes aimed at numerous therapeutic indications.

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The information in this press release should be considered accurate only as of the date of the release. MD Biosciences has no intention of updating and specifically disclaims any duty to update the information in these press releases.

 

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Topics: cancer/tumor

MD Biosciences POP Pain Model Published in European J Pain

Posted by MD Biosciences on Sep 24, 2013 12:41:00 PM

EJP Sept2013 MDBiosciencesMD Biosciences article Characterization of a porcine model of post-operative pain (POP) has been published in the European Journal of Pain, Sept 2013. Dr Sigal Meilin, lead neurologist and research director at MD Biosciences, participated in developing a porcine model of post-operative pain that we propose provides greater translational relevance for the evaluation of local treatments of POP compared with existing rodent models  of incisional pain. 

While the rodent model is commonly used for evaluating POP, one of the major disadvantages is that it is limited in its use in assessing topical and localized treatments such as devices or patches as the hindpaw is relatively small and the rodent may lick or bite at the injured paw. The rodent skin is also very different from human skin in that it heals primarily through contraction rather than re-epithelialization. Pigskin exhibits a higher degree of homology to human skin and has considerable correlation between contractile, metabolic and morphological features in skeletal muscle of human and pig. This model as has three important parameters that can be assessed in parallel:

  • Nociceptor sensitivity
  • Spontaneous behavior
  • Wound healing and inflammation

The following abstract is from the publication in European J Pain, Sept 2013:

Abstract

Background:

Management of acute pain related to surgical intervention, termed post-operative pain or POP, continues to be a major healthcare challenge. While the rat plantar incision model provides valuable data to researchers about the mechanisms mediating POP, the development of topical and localized treatments in small animal models is limited. To help address these issues, we describe here the characterization of a large animal model of incisional pain.

Methods

Pigs underwent full-skin incision or full-skin and muscle incision and retraction (SMIR). Withdrawal thresholds were determined using the Von Frey test at baseline, 0.5–12 h post-surgery and on days 1, 2, 3, 5 and 7 post-surgery. The analgesic effects of systemic morphine [0.1 or 1.0 mg/kg intramuscular (i.m.) dose] and local anaesthetic ropivacaine were studied. Spontaneous pain-like behaviours were scored and analysed. The effects on wound healing were evaluated by gross observation and by histopathological examination.

Results

Pigs incurring SMIR demonstrated significantly increased mechanical hypersensitivity compared with pigs that underwent full-skin incision only (p < 0.05). Maximal analgesia was achieved with morphine (1 mg/kg i.m. dose) at 0.5 h post-treatment. Local treatment with ropivacaine was effective at increasing the withdrawal threshold to Von Frey filaments compared with saline control (p < 0.05) for a period of at least 6 h. Wounds healed normally with no signs of infection, redness or swelling.

Conclusions

We propose that the pig model of incisional pain can provide an appropriate translational model for validating new topical and localized treatments for POP in humans.

 

D. Castel, E. Willentz, O. Donnor, O Brenner, S. Meilin. Characterization of a porcine model of post-operative pain. European J Pain, Sept 2013

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Topics: Pain

IL-23 induced Psoriasis-like Preclinical Model of Inflammation

Posted by MD Biosciences on Aug 8, 2013 7:17:00 AM

MD Biosciences focuses on rapid and cost effective models of psoriasis involving the IL-23/TH17 axis in order to provide companies alternatives to complex and costly xenotransplantation models for screening. With the earlier launch of the IMQ-induced model and now the IL-23 psoriasis model, MD Biosciences offers a range of rapid models for dermal conditions such as dermatitis and psoriasis. 

Recent psoriasis research has focused extensively on the IL-23/TH17 axis. While previously thought to be mainly a Th1 mediated disease, evidence has shifted to a new population of IL-17 producing Th17 cells and the involvement in a variety of autoimmune diseases including psoriasis. The development and maintenance of Th17 cells has been linked to IL-23, a key cytokine involved in the development of autoimmunity. With the focus of research on the IL-23/TH17 role in psoriasis, a number of novel therapeutics are currently in clinical trials that target this pathway.

MD Biosciences is currently working with a biopharmaceutical company in evaluating novel therapeutics that target this pathway. While models of psoriasis such as xenotransplantation models have traditionally been the most commonly used, they are complex and cost prohibitive for screening. MD Biosciences research group has validated rapid and cost effective preclinical models for screening psoriatic therapeutics. In addition to the IMQ-induced psoriasis model launched last year, the most recent model to be validated is the IL-23 induced model of psoriasisform inflammation.

ear thickness data in IL-23 psoriasis modelThe IL-23 psoriasis model is 21 days long and involves the injection of IL-23 into the ear of C57Bl/6, which produces psoriasis-like inflammation that is dependent on IL-22. IL-22 induces keratinocyte proliferation and epidermal hyperplasia contributing to epidermal thickening. “We are continually looking to the most recent research clinical findings. With the number of clinical trials involving targets in the IL-23/Th17 pathway, offering rapid preclinical models of psoriasis involving this pathway allows biopharma companies to cost-effectively screen potentially novel therapeutics. This is important for companies in early discovery to be able to evaluate compounds in a clinically relevant model of psoriasisform inflammation.”

Background on Th17 in psoriasis pathology

While the pathology of psoriasis is not completely understood, there are complex un- derlying mechanisms, which involve the interplay between epidermal keratinocytes, leukocytes such as dendritic cells and APCs, and vascular endothelium. Epidermal keratinocytes and vascular endothelial cells are active participants in the psoriasis inflammatory process via secreted cytokines and growth factors along with the upregulation of signaling and adhesion molecules on their surfaces. TGFb1 is elevated and released by keratinocytes, which when combined with activated dendritic cells is sufficient to generate TH17 cells in skin-draining lymph nodes inducing cutaneous inflammation. Intracellular signaling induces expression of IL-23R on developing Th17 cells promoting responsiveness to IL-23, the key cytokine in the survival and proliferation of Th17 cells. Th17 cells secrete a range of pro-inflammatory cytokines such as IL-6, IL-17A, IL-17F, IL-21, IL-22 and TNF-α . In psoriasis, IL-23 plays an important role with genetic alterations of IL-23p40 and IL-23R leading to enhanced IL-23 production increasing psoriasis susceptibility and indeed injection of the IL-17 supporting cytokine, IL-23, into the skin of mice can induce psoriasis-like inflammation. The main cellular source of IL-17A in psoriasis-like skin inflammation are γδ T cells located specifically in the dermal layers and expansion of Th17 cells producing inflammation and these cells are required to initiate the IL-23 driven processes.

About MD Biosciences

MD Biosciences is a Research Group and Preclinical Contract Research Organization (CRO) providing services and products for biotech/pharmaceutical, medical device and animal health and companies engaged in inflammations & neurology research. With specialized laboratories located in Minnesota, Glasgow, and Israel, our panel of internationally recognized experts provides in-depth expertise and technologies to overcome challenges and provide total solutions to the drug discovery market.

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The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

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Topics: Dermal

Expansion of the US Preclinical Contract Research Lab

Posted by MD Biosciences on Jun 26, 2013 7:48:00 AM

Additional capacity enables MD Biosciences to increase the existing models as well as continue the development of new methods and biomarkers that help bridge the gap between nonclinical data and clinical outcomes.

MD Biosciences, a global preclinical contract research organization (CRO), announces the expansion of its preclinical contract research laboratory in St Paul, MN. The expansion of the laboratory provides additional capacity to increase the in vivo research models of its existing inflammations division. In addition to inflammations models, expansion into the areas of metabolic and cancer research are underway with metabolic studies already being offered. As part of this expansion, MD Biosciences is also hiring experienced scientists in these areas to join our St Paul research team.

As biopharma companies are dealing with reduced R&D budgets and pressures to replace revenue from patent expirations, bringing a clinical mindset to non-clinical study design assists in reducing late phase failures. MD Biosciences is continually developing new methods that help address the gap between non-clinical data and clinical outcomes. Often times existing preclinical models are all that is available but don’t necessarily reflect what is seen in the clinic – additional capacity enables MD Biosciences to continue its R&D program in search of new and more relevant preclinical models and biomarkers.

MD Biosciences currently offers a wide selection of in vivo models within inflammation/autoimmune, CNS, pain, wound healing and cardiovascular fields of research. Its focus is on the cross-talk between the immune and neural systems and the areas of overlap as well as contributions of one to the other in disease pathways. This deep understanding in the cross-talk and a strict focus on sponsors objectives enables MD Biosciences to contribute to the overall study design.

“The expansion of the preclinical contract research lab in the US assists us in serving both North American and International clients. Our global laboratories in the US, UK and Israel are positioned to be able to serve each market and research niche efficiently with strong scientific insight. Our approach to deeply understand each sponsors objectives allows us to contribute and invest scientifically in their program.” says CEO Eddie Moradian.

About MD Biosciences

MD Biosciences is a global preclinical contract research organization (CRO) specializing in the areas of autoimmune, CNS and cardiovascular. Our focus is not only on the science but also on the understanding of our clients’ objectives. This enables us to partner with our sponsors in the project design phase to ensure that studies accurately address the questions being asked. Research facilities are located in the US, UK and Israel – all strategically located within strong scientific and collaborative networks. The flexible, responsive and collaborative approach with a strong scientific understanding of systems cross-talk offers a unique offering to the biopharma community.

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Forward looking statement:

The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

 

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Topics: CRO/outsourcing