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MD Biosciences Blog

Announcing MD Biosciences Neuro, LLC in Cambridge, MA

Posted by MD Biosciences on Sep 3, 2020 10:15:00 AM

We are happy to announce that we have established MD Biosciences Neuro, LLC. in Cambridge, Massachusetts to expand our work and collaborations in the United States. Our team, led by Chief Scientific Officer, Sigal Meilin, is looking forward to developing close partnerships with you and continuing to advance the field of neurology and pain research.
Learn MoreWith a multifaceted approach to assessment of neurological diseases, specializations include pain-related work, neurodegenerative diseases including Parkinson's, neuro-inflammatory diseases such as Multiple Sclerosis (MS), and capabilities in stroke and cerebral ischemia. Preclinical models are complimented by in house histology, biomarker analysis and electrophysiology capabilities. Finally, our unique porcine models share a high degree of similarity to humans, thus offering greater clinical efficacy that serve to augment and accelerate your program towards their next objectives and milestones.


Please contact us with any questions about our services, capabilities, and customizable study design options.

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Topics: Pain, news, Neuro/CNS, Preclinical Discovery, neuropathic pain, Life Science, translational, assays, drug development, preclinical research, disease models, Biotechnology, Behavioral Research, porcine model, Neuroscience

Announcing MD Biosciences Bioproducts, LLC in Oakdale, MN

Posted by MD Biosciences on Sep 2, 2020 12:15:08 PM

We are happy to announce that we have established MD Biosciences Bioproducts, LLC. in Oakdale, Minnesota to expand our work and collaborations worldwide. Our team is dedicated to the development, manufacturing and distribution of life science research products suited for inflammatory and autoimmune diseases, neurology, oncology, pain, and metabolism.

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It is our goal to collaborate with pharmaceutical, biotech, academic and government communities to provide you with the tools needed to optimize your research process enabling you to reach your objectives faster. We offer antibodies, reagents and assays for use in various therapeutic areas of research.

 

                                       Please contact us with any questions about our products and capabilities. 

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Topics: news, Research Products, Preclinical Discovery, Life Science, assays, drug development, clinical research, Biotechnology

MD Biosciences Launches Neuroscience Services Website: featuring neuropathic pain, neurodegenerative disease models and electrophysiology capabilities

Posted by MD Biosciences on Jun 7, 2019 10:20:59 AM

Now live: a website dedicated to MD Biosciences' cutting-edge neurological and CNS research services offered through our Neuroscience Research Laboratories. Our facilities are fitted with state-of-the-art equipment and technologies for preclinical and translational studies, featuring clinically-relevant read outs and endpoints. Specialties include studies of neuropathic, acute and chronic pain and neurodegenerative/neuroinflammatory diseases. Unique pig translational models and electrophysiology capabilities compliment rodent capabilities and accelerate your program towards their next objectives and milestones. Contact our team today! 651-641-1770 or info@mdbiosciences.com 
Visit Neuroscience Services Website

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Topics: Pain, news, Neuro/CNS, in vivo pain models, post-operative pain, Biomarkers, neuropathic pain, Neuropathy, assays, Batch Release Testing, preclinical research, translational research, Electrophysiology, Behavioral Research, porcine model, Neuroscience, Nerve Injury

Now Offering Synaptic Imaging Assay For Cognition and Neurodegenerative Disease Research

Posted by MD Biosciences on Mar 5, 2019 11:18:22 AM

 A powerful method for cognition, learning and degenerative disease research

 

MD Biosciences offers a synaptic imaging assay for evaluating the effect of different treatments on synapse formation and identification. This assay allows the estimation of inhibitory/excitatory synapses ratio and synaptic strength, a powerful method advancing cognition, learning and degenerative disease research and treatment options. 

Screenshot 2019-03-05 10.13.19

Unique Readouts:

  • Synaptic Count
  • Synaptic Strength
  • Identification of synapse type (excitatory/inhibitory)

 

Call or contact us today for more information!

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Topics: Neuro/CNS, assays, Neuroscience, Nerve Injury, cognition research

Senerga Cell-based Assay for Nerve Injury

Posted by MD Biosciences on Feb 19, 2019 11:26:36 AM

 A novel, rapid in-vitro assay for the screening of compound effects                                                              in nerve injury

Neurite outgrowth is the projection and extension of axonal processes from neuronal cell bodies. Through this process, neurons organize themselves into highly-complex functional networks connected synaptically to one another.


Modulation of this neurite outgrowth process (neuritogenesis) has been implicated in a wide range of CNS diseases, including neurodegenerative disorders such as spinal cord injuries, Parkinson’s Disease and Stroke.

 

MD Biosciences has developed a cell-based platform using primary cells extracted from adult rat, to evaluate the effect of tested compounds in the presence of inhibitory factors. The assay’s unique characteristics enable yielding more translatable results, which can serve as a predictive tool of the compounds’ efficacy in older animals and eventually in humans.

MD Biosciences offers an in-vitro assay to evaluate the effect of potential therapeutics on neurite outgrowth and connectivity (synaptic formation) in primary neuronal cell culture. 

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                                                                                     Neurite outgrowth after spinal cord injury in adult animal (Day 7)
Unique Screen Characteristics:

  1. Assays on spinal cord and cortex cell culture
  2. Primary neuronal cells extracted from adult animals
  3. Fast turnaround with results available in approximately 7 days
  4. Primary readout:  number of developed cells and the length of neurites in the presence of the tested compound and vehicle

Call or contact us today for our special introductory price of $1900 per compound. 

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Topics: Neuro/CNS, assays, Neuroscience, Nerve Injury