MD Biosciences Blog

We are happy to announce that we have merged with MLM Medical Labs ("MLM"), a specialized laboratory dedicated to clinical trials headquartered in Germany. With our strong reputation for scientific expertise in immunology and immunological biomarkers and distinguished approach to customer care, our team is looking forward to joining the MLM family, and providing a comprehensive menu of preclinical and clinical services to an extended client base. 

MD Biosciences' life science research products manufacturing and distribution businesses in Switzerland and the US, and MD Biosciences' neurology business focused on preclinical and translational research in neurology in Israel and the US, are not part of this transaction. 

The addition of MD Biosciences follows the acquisition of CirQuest Labs in Memphis, TN earlier this summer, further expanding MLM's geographic reach. The integration of the three organizations will occur in the coming few months to align the operations and quality systems, offering customers access to MLM services in both the United States and Europe. With a stronger and larger global team, "we will have the scale and capacity to support all stages of product development", says Stephan Voswinkel, Managing Director of MLM.

"Joining the growing MLM family is the next step in the evolution of MD Biosciences, Inc., providing an expanded geographic reach in immunology and biomarker testing services. This opens the opportunity to serve MD Biosciences' growing roster of customers with their needs in Europe, the US and with the combined strength of MLM and CirQuest", commented Eddie Moradian, CEO of MD Biosciences.

MLM global services will include: 

• expertise in pre-clinical and clinical research across various therapeutic areas including inflammation, autoimmune, metabolism and oncology
• full-service histopathology lab including immunohistochemistry and digital image analysis 
• specialized biomarker testing
• clinical chemistry
• analyses of drug compounds
• molecular diagnostics 

We look forward to continuing to serve you with an expanded menu of capabilities, supporting all stages of research. To learn more about MLM Medical Labs, visit the website here. 

Despite massive investment in research for treatment options, there are not many effective and safe therapeutics for human chronic neuropathic pain (NP) afflictions. Options are limited due to the lack of translatable animal models, especially large animals who have similar physical and metabolic features to humans (Rice et al., 2008, Henze and Urban, 2010, Swindle et al., 2012). MD Biosciences, Inc. has developed a modified unilateral sciatic nerve PNT model in pigs that produces sustained NP behaviors consistent with those observed in human pain patients. The pig PNT model provides highly valuable data for translational pain research. 

                          Read more in our scientists' latest publication here! 

MD Biosciences translational models can be enhanced with behavioral analysis capabilities, electrophysiology recordings, histology/IHC services and more. Contact us today for more information: info-us@mdbiosciences.com or (651) 641-1770.

 MD Biosciences has extensive experience in the application of immunohistochemistry to analysis of markers of interest in tissue. Our validated protocols permit such assessments as lymphocyte analysis, cellular proliferation, cellular activation/differentiation, inflammation, biomarker analysis, and much more.

View high-resolution whole slide image examples of our IHC staining results below!

https://www.mdbhistopath.com/immunohistochemistry-image-gallery-ihc-markers 

Don't see a marker you're interested in? We provide custom IHC assay development and validation using either commercially available or Sponsor-provided antibodies, and additionally have in-house antibody development facilities for challenging targets. Contact us to discuss a custom project! 

Below is a sample staining that demonstrates anti-CD3 IHC, 2x. CD3 is the T-cell co-receptor and is considered a Pan-T Cell lineage marker. T cells are seen surrounding B Cell Follicles in the below tonsillar tissue, demonstrating rich T-cell zones and interspersed t-cells within follicles. More high IHC quality images available upon request, and pathology review available in house.

Call us today for your histology needs: (651) - 451-1770.

Our new histopathology website is now live! Check it out here!

MD Biosciences Laboratories offer a broad range of histology, immunohistochemistry (IHC) and In-situ hybridization services, staining services, tissue processing and digital pathology to enhance readouts and study applicability to the clinic.

We operate two distinct histology and IHC laboratories, including a GLP developmental research laboratory and a CLIA clinical IHC laboratory, offering a broad range of state-of-the-art technical capabilities to meet research and clinical study needs. Method development and optimization in addition to routine analysis shapes the foundation for our tissue-based services. The laboratories are equipped with advanced automated staining systems and digitized imaging, facilitating the privileged access to large, annotated image files. Services are complimented by the Visiopharm artificial intelligence-based image analysis platform to enhance the quality and speed of analysis. Services are supported by expert consultant pathologists specialized in various areas. 

Contact us to learn more about our services!