MD Biosciences Blog

MD Biosciences Announces Release of Zika Virus Diagnostic Test

Posted by MD Biosciences on Feb 29, 2016 2:00:00 PM

Zika Virus Test Update: Saint Paul, MN March 10, 2016

MD Biosciences announces that it will proceed with the Zika test services following clarification with the FDA regarding any pre-market approval requirements pertaining to this assay. Testing services will not be offered pending this clarification.

 

Saint Paul, MN, USA - February 29, 2016, - MD Biosciences, Inc. (mdbiosciences.com) Clinical and Diagnostics Services Laboratory announces the release of its rapid assay to detect the virus in human blood and urine samples. The nucleic acid test can be performed in a few hours in blood, plasma, serum or urine samples. The test is specific for the Zika virus and was shown not to cross react with other infectious viruses such as Dengue, West Nile or Chikunguya. The laboratory developed test is available immediately

The World Health Organization stated that the spread of the mosquito-borne virus will grow explosively throughout the Americas. According to the CDC, the virus has also been shown to be transmitted through sexual contact. Upwards of four million infections are expected in the region. Close to 80% of infections are asymptomatic while others suffer from fever, rash, joint aches and other hallmarks. A steep increase in birth defects and Guillain-Barre syndrome has correlated to the spread of the virus. The explosive spread of the virus, along with major crowd and traveller-related events such as this year’s Olympic Games in Brazil, have underscored the need for steps in fighting the spread of the virus, including the ability to rapidly and specifically identify the infection.

Eddie Moradian, Chief Executive Officer at MD Biosciences, stated, “We are extremely proud of our CLIA diagnostics laboratory’s ability to provide a reliable, accurate and rapid method of testing for Zika virus. This demonstrates our commitment in placing our expertise, knowledge and infrastructure for the betterment of health, in the US and throughout the world, whether through the development of more advanced diagnostics or by advancing newer, better and more efficient therapies."

 

About MD Biosciences

MD Biosciences is a leading provider of clinical and preclinical services with over 25 years of experience in the clinical diagnostics and preclinical research areas. Services are provided for cancer, inflammatory, metabolic and neurological diseases. MD Biosciences laboratories provide extensive experience in working with biomarkers and developing validated laboratory assays. MD Biosciences operates through its facilities and laboratories in the United States, Switzerland and Israel.

Located in Saint Paul, MN, MD Biosciences' Clinical and Diagnostics Services Laboratory is a CLIA accredited laboratory for high complexity testing. All testing is performed under stringent guidelines in state of the art laboratories. Other services include clinically relevant tests for genetic markers of diseases including various cancers.

Inquiries may be directed to: Susan Belzer, Vice President, MD Biosciences Clinical Diagnostics Laboratory

by e-mail: [email protected]

by telephone to 1-888-USMDBIO (1-888-876-3246) or (651-641-1770).

 

Read More

Topics: news, Preclinical Discovery, Zika, Virus Test

MD Biosciences Announces Addition of Cancer Suite

Posted by MD Biosciences on Jan 28, 2016 4:28:59 PM

ST. PAUL, Minnesota - January 25, 2016 - MD Biosciences (mdbiosciences.com) today announced the addition of its suite of in vivo and in vitro cancer models to its family of preclinical contract research services. MD Biosciences' oncology research program specializes in murine solid tumors for subcutaneous and orthoptopic models (for example, advanced breast cancer and renal cancer) with a specific focus on the immune aspects of disease development and progression. The comprehensive services include both syngeneic and xenograft models with readouts for longitudinal tumor monitoring (for some models), longitudinal blood phenotyping (immune cell distribution, biomarkers, etc.), endtime-point primary/metastic tumor evaluation, tumor tissue-specific cellular analysis using intravascular staining (cells: epithelial, endothelial, immune, etc.), biomarker analysis (blood, tumor, tissue, spleen, lymph node, etc.) and histological grading and evaluation of tumor specific issue (H&E, IHC, etc.).

"Our onco-immunology research team is comprised of skilled scientists with deep-rooted expertise in a highly complex field," said Eddie Moradian, MD Biosciences CEO. "We at MD Biosciences are excited to bring our high level of expertise and our novel models to assist sponsors and partners in reaching their programs' developmental goals. This new suite of capabilities compliments our existing, best-in-class services in other disease areas.

 

About MD Biosciences

MD Biosciences is a leading provider of preclinical services in the core areas of inflammation, immunological, neurologoical and metabolic diseases. The suite of services includes a wide range of cell-bassed assays, in vivo disease models, translational models as well as models for the indentification of the mode of action of drugs. The services are supported by CLIA accredited and GLP in vitro diagnostic laboratories for the testing of samples by using genomic and proteomic methods. MD Biosciences' in vitro laboratories provide services for the testing of clinical samples. Proprietary models include pig models for neuropathic pain, would healing and other key disease areas.

 

Read More

Topics: news, in vivo pain models, cancer/tumor, contract research

MD Biosciences & Janssen R & D, LLC to screen extensive library of compounds.

Posted by MD Biosciences on Apr 14, 2014 8:00:00 AM

MD Biosciences enters into an agreement with Janssen Research & Development, LLC to screen an extensive library of compounds with its proprietary Senerga® Phenotypic Screening Platform.

 

St Paul, MN (April 14, 2014) – MD Biosciences announces that it has entered into a research agreement with Janssen Research & Development, LLC, through the Janssen Incubator and a venture team focused on natural product drug discovery programs, to screen a novel and proprietary chemical library of compounds for pharmaceutically relevant activity.  MD Biosciences will apply its innovative screening platform, Senerga® Phenotypic Screening Platform for this purpose. Senerga® PSP is based on three matrices covering  pathways related to inflammatory, metabolic, cardiovascular and CNS diseases in addition to delivering preliminary toxicology data. Senerga® PSP delivers a comprehensive portfolio of phenotypic and biomarker data for each compound in the library and points towards putative mode of action of novel compounds. A dedicated scoring algorithm is used to rank compounds with regards to their activity. Pharmaceutically active compounds will be validated in dedicated disease models. The use of Senerga® PSP provides unique speed and efficiency in mining its novel chemical library.

 

About the Senerga® Screening Platform

MD Biosciences has in-depth expertise and data on complex programs involving mechanism of action and efficacy studies. Senerga®PSP provides a uniquely customized approach applicable to new compounds as well as for repositioning of failed or on-market drugs. Senerga® is available for collaborative development programs together with pharmaceutical and biotechnology companies.

 

About MD Biosciences

MD Biosciences is dedicated to the preclinical discovery and development of compounds. The company engages in collaborative partnerships and research projects with pharmaceutical and biotechnology companies world wide. MD Biosciences operates purpose-built and state-of-the-art facilities in Nes Ziona, Israel and in St. Paul, MN, USA.

 

 

--------------------

 

The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

Read More

Topics: CRO/outsourcing, news

MD Biosciences Receives AAALAC Accreditation

Posted by MD Biosciences on Mar 19, 2014 12:59:00 PM

Wednesday, March 19, 2014, St. Paul, MN – MD Biosciences, a drug discovery and development services provider, is pleased to announce it has been give full accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC). Accreditation for the St Paul facility was awarded following an extensive on-site assessment by representatives of the Council on Accreditation, which stated that MD Biosciences “provides and maintains an excellent program of laboratory animal care and use” with particular noteworthiness in the program alignment with quality animal care and use, comprehensive occupational health and hazard reduction, high level of attention to detail in documentation and standard operating procedures as well as staff training programs and a high level of expertise among the personnel. 

 

“We are very pleased to receive accreditation from AAALAC, recognizing that only 900+ institutions worldwide carry this accreditation. MD Biosciences prides itself on high standards both in scientific methods and animal care. This accreditation provides our clients assurance of our commitment to compliance with industry and regulatory guidelines for high standards of animal care and handling” said Eddie Moradian, CEO of MD Biosciences. Researchers can read further about the benefits of accreditation here.

 

MD Biosciences is also committed to its continuing development and expansion of services it offers its clients and partners from its multiple laboratories. In addition to specialized efficacy studies and the development of more clinically relevant models, MD Biosciences also offers its partners customized screening programs aligned with clients’ specific business goals.

 

 

 About AAALAC International

AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC stands for the "Association for Assessment and Accreditation of Laboratory Animal Care." More than 900 companies, universities, hospitals, government agencies and other research institutions in 37 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. These institutions volunteer to participate in AAALAC's program, in addition to complying with the local, state and federal laws that regulate animal research.

www.aaalac.org

 

About MD Biosciences

MD Biosciences is a leading preclinical research group and contract research organization (CRO) working with biopharmaceutical and medical device companies in an effort towards progressing discovery and development programs to clinical stages. We are deeply focused on inflammatory, neurodegenerative/CNS, pain, dermal, metabolic and cardiovascular conditions with a particular emphasis on the interplay between the immune, nervous and cardiovascular systems and the conditions that arise in the cross talk between them. We bring decisive value to our clients’ programs with the extensive experience gained over many years of handling different compound classes and numerous therapeutic indications. MD Biosciences operates three state-of-the-art laboratories across the globe equipped with highly specialized infrastructure, equipment, methods and scientists with expertise in therapeutics areas. Find out more about MD Biosciences and the services offered at www.mdbiosciences.com.

 

--------

 

The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

Read More

Topics: CRO/outsourcing, news

MD Biosciences Screens Large Pharma Co. Compounds w/its Senerga® Platform

Posted by MD Biosciences on Nov 4, 2013 1:49:00 PM

St Paul, MN  – MD Biosciences announces that it has entered into a research agreement with one of the Top 10 pharma companies for screening a library of compounds. MD Biosciences will apply its innovative screening platform, Senerga®, to the pharma company’s compound library with the primary objective of increasing the chances of discovery efficacy on a broader and more efficient basis. These compounds can then be selected based on pharmaceutically relevant activity to be further developed by the sponsor.

 

 “Exploring novel, high-value applications for compounds based on our Senerga® Platform is the core strength of MD Biosciences. We are very excited about this compay engaging MD Biosciences in this important program. It is a great company, sharing our vision in evolving new and efficient ways in the discovery process” said Eddie Moradian, CEO of MD Biosciences.

 

About the Senerga® Screening Platform

MD Biosciences has a long history of working on complex programs for mechnism of action screening, and efficacy. By conceptualizing a platform that provides algorithmic analysis of a combination of efficacy, biomarker, mechanistic and safety/behavior data, clients are able to broadly screen compounds on the basis of effects on cells, tissues and whole organisms in disease modification without the necessity of prior knowledge of therapeutic pathways. Senerga® screening is a customized approach through in vitro and in vivo models selected to give the broadest screen based on the compound library.

 

About MD Biosciences

MD Biosciences is a global preclinical research group and contract research organization (CRO) working with biopharmaceutical and medical device companies in an effort towards progressing discovery and development programs to clinical stages. MD Biosciences provides a broad range of services focused in inflammatory, neurodegenerative/CNS, pain, dermal, metabolic and cardiovascular conditions with a particular emphasis on the interplay between the immune, nervous and cardiovascular systems and the conditions that arise in the cross talk between them. Utilizing innovative approaches to efficacy and screening models, MD Biosciences has played a key role for our clients in multi-year programs that have involved respositioning/developing compounds, out-licensing compounds and screening compound libraries. MD Biosciences diverse portfolio of clients includes some of the world’s largest and most well-known pharmaceutical and biotechnology companies.

--------------------

 

The information in this press release should be considered accurate only as of the date of the release. MDB has no intention of updating and specifically disclaims any duty to update the information in these press releases.

Read More

Topics: news