MD Biosciences Blog

MD Biosciences lab was featured with Ellegaard offering an exclusive expertise in pain studies. The article discusses our work to develop and validate models in adult pigs, specifically for chronic and acute pain.

When do we recommend to work with minipigs?

MD Biosciences pigs studies include domestic pigs and Göttingen minipigs.

The main advantage of the minipig is that it gains weight much slower than the domestic pig. This could be significant when:

• The study requires working with adult animals
• When we run models with chronic diseases ( ≥3 months)
• Tox and ADME studies are run in Göttingen minipigs, which is significant for standardization

Pig models at MD Biosciences: 

Post-Operative Pain

Modified Post-Operative Pain

Neuropathic Pain

Wound Healing

Ready to learn how your research can accelerate with pig studies? Contact us today! +1 (651) 641-1770 or info-us@mdbiosciences.com 

Now live: a website dedicated to MD Biosciences' cutting-edge neurological and CNS research services offered through our Neuroscience Research Laboratories. Our facilities are fitted with state-of-the-art equipment and technologies for preclinical and translational studies, featuring clinically-relevant read outs and endpoints. Specialties include studies of neuropathic, acute and chronic pain and neurodegenerative/neuroinflammatory diseases. Unique pig translational models and electrophysiology capabilities compliment rodent capabilities and accelerate your program towards their next objectives and milestones. Contact our team today! 651-641-1770 or info@mdbiosciences.com 

Proud to announce that the pig post operative pain model pioneered by our scientists was used and cited in a clinical study poster publication written by Heron Therapeutics to assess the synergistic effect of Bupivacaine and Meloxicam in HTX-011.

"Meloxicam and Bupivacaine combined in a single extended-release formulation (HTX-011) delivered at the wound site in a preclinical post-surgical pain model in pigs exhibited greater analgesia than either compound delivered alone within the same extended-release formulation; this finding was confirmed in an initial clinical trial in bunionectomy" (Heron Therapeutics, 2018).

To learn more about our rodent and pig post-operative pain models, visit our preclinical pain webpage or view  our datasheet below.

 MD Biosciences will be presenting its newest advances in translational pig models for pain at this year's SMi Pain Therapeutics Conference to be held in London, UK on May 22-23. Translational models in pigs for the study of pain have become an indispensable tool in drug development. The skin structure of the pig, particularly with respect to its neuronal structure, shows a high degree of similarity to that of humans. This provides a platform in which new therapeutics can be tested to yield results which are highly predictive of human outcomes. MD Biosciences has continuously developed its models to approximate the human condition as closely as possible, bringing its unique capabilities to the drug development process. Please contact MD Biosciences or SMi Group Ltd for conference details.