occlusion-induced myocardial infarct, preclinical contract research 

Myocardial I/R whitepaper

Evaluating Myocardial Protection of therapies in preclinical IR models

The occlusion-induced myocardial infarct model is a well-known technique for investigating the cardio-protection of a drug or device in the event of ischemia/reperfusion injury. The advantage of the model is the ability to study the functional relevance of a treatment on the heart following direct coronary flow and the mechanimsms by which the treatment promotes myocardial protection.

myocardial infarct

Download the whitepaper to learn more:

  • Overview of the model
  • Histological analysis of the heart and infarct size
  • Blood biomarkers