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Preclinical Contract Research

MD Biosciences offers in vitro and in vivo services preclinical contract research services for efficacy studies in the drug discovery phase. Our services include various in vivo disease models, complex mode of action platforms and biomarker analysis using all available methods. Combined in vivo and in vitro protocols can be performed making complex study designs possible.    What sets us apart from traditional service providers? At MDB, we invest time into customizing protocols to meet your individual needs. We learn and understand your objectives, hurdles and milestone requirements. We have access to a wide network of contracted experts within our areas of core competence allowing us to contribute suggestions and alternatives to tackle the obstacles challenging your business. We view your business as a whole and not as series of singular projects. We reach your milestone needs with lower over-all costs to your enterprise. We help you succeed better in today’s business environment. Simply contact us to discuss how we can help you transform your company, respond quickly to opportunities, and reach your objectives more quickly and effectively. Our experimental services are provided in both GLP and non-GLP standards. Markets Served: Bio/Pharmaceutical Drug Discovery Within this industry, we provide a range of preclinical services for evaluating saftey and efficacy of proposed therapies. Our goal is to combine in vitro and in vivo studies to give you a well-rounded platform of testing in both a human cell system that closely mimics the human situation as well as in vivo animal models for efficacy. This strategy serves to contribute to more detailed information and mode of action information on a test compound, thereby potentially eliminated late phase failures. Inflammation Models Neurology Models Mode of Action Platforms In vitro cell based assays Medical Device Industry Within this industry we provide a range of testing for both implantable devices as well as inflammatory effects of coated delivery systems. Cell Growth on stent material in vitro assays Contact dependant/Independant Assay Post-operative models Cardiac infarct models Animal Health and Nutrition There is a great deal of interest in the companion animal health research area, particularly related to arthritis and bone health, obesity, and renal and liver function. Despite this interest, many biomarker assays that have been established for health monitoring and preclinincal studies have yet to be developed for use with canine or feline samples. To fulfill the need for biomarker assays, we have developed and validated a panel of canine and feline biomarker assays.

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