MD Biosciences has developed a unique post-operative (incisional) model to meet this growing research need and allows for the assessment of local and systemic therapies. Models of Post operative (incisional) pain are appropriate for evaluating implants, patches, medical devices and creams. Don't see the model or assessment you require? Our scientists are experienced with rapidly validating models from the literature. Please speak with a scientist to discuss your requirements.
MD Biosciences offers both the rodent and a porcine model of POP. The porcine POP provides greater translational relevance for the evaluation of topical and local treatments. We have published the characterization of the model in the Eur J Pain (European Journal of Pain, Sept 2013, Characterization of a porcine model of post-operative pain, Dr Sigal Meilin, MD Biosciences)
IHC Staining of Transverse Porcine Skin Sections Using PGP9.5 Antibody Demonstrating Peripheral Nerves
Figure A. High magnification of PGP9.5-positive nerve branches in the dermis. Figure B. High magnification of PGP9.5-positive nerve branches in the subcutaneous fat layers