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Collagen antibody-induced Arthritis


A rapid and synchronized alternative to the CIA and K/BxN models that reduces variability, eliminates the need for expensive colonies and conserves test compound, controls and vivarium space.

The collagen antibody-induced arthritis model (CAIA) is an excellent alternative model for evaluating compounds for efficacy in rheumatoid arthritis. Companies no longer need to wait 42 days for results or carry special colonies as is the case in the Collagen-induced arthritis (CIA) model and the K/BxN models respectively.


Download the whitepaper to learn more about the benefits of the anti-collagen induced arthritis model:


  • Eliminate variability
  • No expensive colonies
  • Synchronized disease
  • Results in 12 days
  • Susceptible in a variety of strains including C57BL/6

Download Whitepaper