Collagen antibody-induced arthritis whitepaper, preclinical contract research, efficacy study

CAIA whitepaper

Collagen Antibody Induced Arthritis Whitepaper

Tired of waiting 6 weeks for results?

The collagen antibody-induced arthritis model (CAIA) is an excellent alternative model for evaluating compounds for efficacy in rheumatoid arthritis. Companies no longer need to wait 42 days for results or carry special colonies as is the case in the Collagen-induced arthritis (CIA) model and the K/BxN models respectively.

Download the whitepaper to learn more about the benefits of the anti-collagen induced arthritis model:

  • Eliminate variability
  • No expensive colonies
  • Synchronized disease
  • Results in 12 days
  • Susceptible in a variety of strains including C57BL/6

 

Optimized to use less antibody with C57Bl/6

Hyperplasia and cellular infiltration

The use of transgenic strains often require higher amounts of induction reagents or altered protocols to achieve acceptable levels of disease. MD Biosciences has optimized the ArthritoMab™ antibody cocktail for use in transgenic strains to eliminate the need for substantially higher amounts of antibody.