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Parkinson's Disease Models


What Animal Models of Parkinson’s Disease Have Revealed About Pathogenesis and Treatment.

A closer look at classical models of Parkinson's: 

Parkinsons-60HDA-preclinical-efficacy-mdbiosciences-CROThe 6-OHDA and acute MPTP models for Parkinson's Disease have been well characterized with the underlying mechanisms of toxicity well understood. Both models are useful in evaluating potential neuroprotective therapies providing the ability to target any differences in motor activities and determine whether a drug differentially affects a specific motor behavior.


Download the whitepaper to learn more:
  • Background of Parkinson's Disease and current research
  • Overview of classic in vivo models: MPTP and 6-OHDA
  • Data and typical models
  • Therapies of Parkinson's Disease