Whitepaper:

CCI or SNL?

 Choosing preclinical peripheral nerve injury models.

Understanding the mechanisms underlying neuropathic pain syndromes is crucial to the development of more effective therapies.

Neuropathic pain may arise from many different disease states and present with a variety of symptoms, including shooting or burning pain, tingling, numbness and allodynia. Understanding the mechanisms underlying neuropathic pain syndromes is crucial to the development of more effective therapies.

 

Download the whitepaper to learn about two common peripheral nerve injury models, Spinal nerve ligation and Chronic Constriction Injury:

 

Peripheral-nerve-injury-whitepaper-mdbiosciences-preclinical-CRO
  • Overview of each model
  • Typical protocols and data
  • Similarities and differences
  • Observable pain behaviors
  • Contributing mechanisms
  • Relevant positive controls

 

 

Both the CCI and SNL are well-established peripheral nerve injury models used to study neuropathic pain. Gain an understanding on the key differences determining which model is most suitable for use.