It's Tuesday, which means MD Biosciences is providing coverage of the latest fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. This week's blog is compiling posts from science journals including LinkedIn, Mayo Clinic, ScienceDaily, Nature Communications, The Journal of Immunology and Nature Biotechnology. Skim the titles below to catch up on what is happening and follow the links to read more about something that catches your eye!
The clinical use of 7-Tesla MRI is significantly enhancing researchers at Mayo Clinic ability to manage brain and peripheral nerve tumors, seizure disorders and other neurological disorders. This specific type of MRI is demonstrating an unrivaled ability to detect structural abnormalities that are not typically observed in lower magnet strength MRI machines. Reported by Mayo Clinic.
A new digital drug discovery tool has been developed by Insilico Medicine, aiming to extend lifetimes and improve health through aging research and drug discovery. A new machine is being used to explore signatures of diseases, identifying the most promising protein targets and matching perfect molecules for such. AI technology is such a valuable tool for decreasing the length of timelines for treatment options and knowledge of disease onset. Reported by LinkedIn.
Unraveling Cell Death Pathways
We know cell death is vital for overall health; without it, humans are at risk for developing a plethora of autoimmune diseases, cancer and more. Researchers at Thomas Jefferson University are discovering a new role for a TRADD, one of the essential molecules involved in cell death. This discovery is key for informing various fields including autoimmunity, oncology and in vivo research. Published in Nature Communications.
An Inside Look Into the Immune System and its Communication Patterns
A study reported by University Health Network and ScienceDaily conducted by Dr. Tak Mak (known for cloning the human T-cell receptor) demonstrates that immune cells in human bodies are creating brain chemicals to fight off infections. This discovery will lead to the next research goal: identifying key receptors to target that facilitate communication between diseased areas of the body and immune cells.
Imbalances in the human gut microbiome contributes to complex diseases, most of which are rooted in inflammatory conditions including inflammatory bowel disease, irritable bowel syndrome and obesity. Since bacteria can be quite difficult to grow and maintain, there is not eroding knowledge on the topic, which is what inspired Dr. Forster and colleagues from Wellcome Sanger Institute to study 20 fecal samples of UK and Canada adults. Their analyses revealed 737 bacterial strains, of which 273 were separate bacterial strains and 173 of those had never been sequenced before. Reported by Sci News and published in Nature Biotechnology.
The Journal of Immunology published a report of scientists uncovering key roles of LACC1 in inflammatory conditions. Follow the link in the title to learn more!
Hope you enjoyed this week's top finds! Check back next week for more and always feel free to reach out with study inquiries.