Immunogenicity

In Vivo & In Vitro Assays

Evaluate the Immunosuppression or Immunogenicity Properties of Compounds 

ImmuneProfiler is a suite of assays that can be customized to determine a compounds properties on the immune response. We offer a variety of in vivo models and in vitro assays for evaluating select pathways. Sponsors can select pathways of interest, choose between stimulation or inhibition assays, evaluate in cell based or whole animal systems.

Readouts include:

• Specific cytokine panels, FACs analysis
• Investigation of Th1 Th2, Th17, CD8, B-cell response in vivo
• In vitro methodologies and efficacy testing evaluating macrophage and T-cell inhibition and stimulation, proliferation and cytokine release

In Vivo Immune Response Models:

In Vitro Immune Response Assays