Experts in Inflammatory Pathways, Disease Models and Biomarker Analysis
Talk to us about your objectives! We offer validated models of many inflammatory diseases including skin (IL-23 psoriasis, dermatitis, delayed type hyper-sensitivity, anaphylaxis), gastro-intestinal (TNBS or DSS induced IBD), respiratory (acute lung injury, asthma, fibrosis), joint (rheumatoid arthritis) and sepsis (LPS induced). Each disease area is served by different models, offering answers to your candidate therapeutic's effect on different disease parameters. Our inflammatory disease models serve as the basis for in-depth biomarker analysis, providing unrivaled ability to nuance the effect of compounds at each disease stage.
Our expert scientists are able to combine different disease models to offer unparalleled ability to distinguish the mode of action of novel compounds. Combining models, such as IBD, fibrosis or asthma, along with biomarker read-outs (proteins, RNA expression, histology) may quickly and cost-effectively reveal a putative mode of action.
We constantly invest in the development of new models. Are you interested in a variation of a model or a new paradigm? Speak with us! We are always interested in co-development and pilot programs to establish new models and reaching new levels of understanding.
What will we bring to your project?