Inflammatory Joint Disease Models
Rodent models of immune-mediated arthritis (RMIA) are commonly used to evaluate the mechanisms of inflammatory joint disease, as well as test the efficacy of anti-arthritic compounds. Collagen induced arthritis (CIA) and adjuvant induced arthritis (AIA) are two commonly used models for this purpose. At MD Biosciences we offer our clients the novel and rapid collagen antibody-induced arthritis (CAIA) model as well.
Our expertise includes:See below information to learn more about our experience/readouts/options:
|Biologics||Arthritis score||Biomarkers (protein, mRNA)|
|NCEs||Paw thickness||Cell populations by FACS|
|Plant-based compounds||Body Weights||Histology/IHC|