In-Situ Hybridization (ISH) and Immunohistochemistry (IHC) Services |
| Understanding biomarker expression patterns visually within tissue is crucial to our understanding overall physiology, allowing us to better perceive and diagnose diseased states. Both immunohistochemistry (IHC) and RNA in situ Hybridization (ISH) provide images allowing for assessment of localization and quantification of marker expression, while preserving the tissue integrity. IHC and ISH can be used together to validate data or provide complementary information. The combination of both technologies can provide unique information. It can identify a secreted protein (like growth factors or cytokines) and its origin, identifying both the original cell and protein within the tissue sample. ISH can also be used for detection and quantification of the RNA target inside the tissue. The simultaneous analysis of RNA and protein expression of the same target genes allows for the identification of potential gene expression regulation mechanisms. MD Biosciences offers fully automated IHC and ISH testing, which can be performed using both brightfield and immunofluorescence staining as singleplex or multiplex assays. In addition, we have the capability to combine IHC/ISH testing, allowing for protein/gene expression comparison simultaneously. With whole slide imaging and hosting capabilities, remote viewing, annotation and downloads are easily accessible. Moreover, we offer pathologist review and/or quantitative AI-powered image analysis. 
How can our histology team assist with your research? Contact a scientist to discuss customized options that fit your needs! |
Read More
Topics:
Biomarkers,
Pathology,
ID Markers,
clinical research,
clinical diagnostics,
Biotechnology,
Histology,
GLP,
Artificial Intelligence
A message from our laboratories to yours: during these times of economic and personal hardship, we want to extend our sincerest support and hope you are keeping well.
Read More
Topics:
Cytokines,
assays,
drug development,
clinical research,
Biotechnology,
COVID-19
It's Tuesday, which means MD Biosciences is providing coverage of the latest fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. This week's blog is compiling posts from science journals including Nature Medicine, Nature Genetics, Medical Xpress, PM360, ScienceDaily and Science. Skim the titles below to catch up on what is happening and follow the links to read more about something that catches your eye!
Read More
Topics:
Inflammation,
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Metastatic tumor,
Immuno-Oncology,
preclinical research,
Biotechnology,
Neuroscience
It's Tuesday and we're back with covering the latest fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary area. This week's blog is providing up-to-date news coverage compiling posts from science journals including Advanced Materials, Cell, EurekAlert, ScienceDaily, Proceedings of the National Academy of Sciences, News Medical and Nature Biomedical Engineering. Skim the titles below to catch up on what is happening and follow the links to read more about something that catches your eye!
Read More
Topics:
Inflammation,
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Metastatic tumor,
Immuno-Oncology,
preclinical research,
Biotechnology,
Neuroscience
Happy New Year from the team at MD Biosciences! This week's blog is providing up-to-date news coverage compiling posts from science journals including Advanced Materials, Cell Reports, Clinical OMICS, Gen News, Neuroscience News, and Science Advances reporting fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. Skim the titles below to catch up on what is happening and to learn some of the top predicted biotechnology trends for 2019! Follow the links to read more about something that catches your eye!
Read More
Topics:
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Immuno-Oncology,
Biotechnology,
Neuroscience
MD Biosciences providing up-to-date news coverage compiling posts from science journals including Gen News, Sci News, ScienceDaily, Stanford Medicine, Nature Communications, & eLife reporting fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. Skim the titles below to catch up on what is happening and to learn what the team at MD Biosciences is reading about. Follow the links to read more about something that catches your eye!
Read More
Topics:
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Immuno-Oncology,
Biotechnology,
Neuroscience
MD Biosciences providing up-to-date news coverage compiling posts from science journals including Eurek Alert, Gen News, Sci News, ScienceDaily, Nature Communications, & Proceedings of the National Academy of Sciences reporting fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. Skim the titles below to catch up on what is happening and to learn what the team at MD Biosciences is reading about. Follow the links to read more about something that catches your eye!
Read More
Topics:
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Immuno-Oncology,
Biotechnology,
Neuroscience
MD Biosciences providing up-to-date news coverage compiling posts from science journals including Cell Stem Cell, Gen News, News Scientist, Nature Communications & Business Insider reporting fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. Skim the titles below to catch up on what is happening and to learn what the team at MD Biosciences is reading about. Follow the links to read more about something that catches your eye!
Read More
Topics:
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Immuno-Oncology,
Biotechnology,
Neuroscience
MD Biosciences providing up-to-date news coverage compiling posts from science journals including Alzheimer's Research and Therapy, Journal of Experimental Medicine, News Scientist, ScienceDaily, & Sci News reporting fascinating and innovative discoveries happening all over the world across a wide variety of disciplinary areas. Skim the titles below to catch up on what is happening and to learn what the team at MD Biosciences is reading about. Follow the links to read more about something that catches your eye!
Read More
Topics:
Neuro/CNS,
cancer/tumor,
Biomarkers,
Academic Research,
Immuno-Oncology,
Biotechnology,
Neuroscience
